Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 2.953


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX1chr10_+_1028810500.769.2e-04Click!
TLX3chr5_+_1706688920.058.6e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_+_45699830 9.651 NM_030582
NM_130444
 COL18A1

collagen, type XVIII, alpha 1

chr22_+_40093245 8.556 NM_001145398
 TEF
thyrotrophic embryonic factor
chr17_-_77394872 8.092 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_+_1580504 6.515 WDR81
WD repeat domain 81
chr17_+_74542066 6.470 NM_198593
 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr16_-_30032330 6.257 NM_024307
 GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr2_-_217268492 6.198 NM_000599
 IGFBP5
insulin-like growth factor binding protein 5
chr12_-_54392328 6.190 NM_001144997
 ITGA7
integrin, alpha 7
chr19_+_15612706 4.100 NM_000896
 CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr1_-_16217025 4.007 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr15_-_38420414 3.891 NM_207380
 C15orf52
chromosome 15 open reading frame 52
chr11_-_62213577 3.803 LRRN4CL
LRRN4 C-terminal like
chr8_-_22044463 3.754 NM_005144
NM_018411
 HR

hairless homolog (mouse)

chrX_-_53327473 3.695 NM_015075
 IQSEC2
IQ motif and Sec7 domain 2
chr2_+_96818048 3.564 CNNM4
cyclin M4
chr7_-_16811131 3.531 NM_006408
 AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr12_-_50871953 3.457 NM_001081492
NM_182507
 KRT80

keratin 80

chr9_+_35663852 3.448 NM_001216
 CA9
carbonic anhydrase IX
chr17_-_74487527 3.407 NM_005567
 LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr9_+_139241838 3.386 NM_001190228
 LOC643596
hypothetical LOC643596

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.07 3.33e-02 GO:0032535 regulation of cellular component size

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.08 4.50e-03 GO:0005578 proteinaceous extracellular matrix
2.04 1.70e-03 GO:0031012 extracellular matrix
1.68 6.54e-05 GO:0044421 extracellular region part
1.45 9.34e-05 GO:0005576 extracellular region

Nothing significant found in function category.